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CDK4 PROTEIN KINASE
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase 4
Descriptor
Spanish
:
cinasa 4 dependiente de la ciclina
Descriptor
Portuguese
:
Quinase 4 Dependente de Ciclina
Synonyms
English
:
Cdk4 Cyclin Dependent Kinase
Cdk4 Cyclin-Dependent Kinase
Cdk4 Protein
Cdk4 Protein Kinase
Cell Division Protein Kinase 4
Cyclin D Dependent Kinase CDK4
Cyclin D-Dependent Kinase CDK4
Cyclin Dependent Kinase 4
Cyclin-Dependent Kinase, Cdk4
PSK J3 Kinase
PSK-J3 Kinase
Protein Kinase, Cdk4
p34PSK J3 Kinase
p34PSK-J3 Kinase
Tree Number:
D08.811.913.696.620.682.700.646.500.875
D12.644.360.250.451
D12.776.167.200.451
D12.776.476.250.451
Definition
English
:
Cyclin-dependent kinase 4
is a key regulator of
G1 PHASE
of the
CELL CYCLE
. It partners with
CYCLIN D
to phosphorylate
RETINOBLASTOMA PROTEIN
. CDK4 activity is inhibited by
CYCLIN-DEPENDENT KINASE INHIBITOR P16.
History Note
English
:
2006(1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50715
Unique Identifier:
D051358
Occurrence in VHL
:
Similar:
DeCS